Ryan, Yuxin LI (李雨鑫)

MSc in Computer Science at The Chinese University of Hong Kong

Bsc in Computer Science at CUHK, minor in Statistics

Email: ryanli[at]link[dot]cuhk[dot]edu[dot]hk

Biography

Yuxin LI (Ryan) is currently biocomputation researcher at Baidu Biocomputation Lab. He obtained his Master of Science degree in Computer Science at the Chinese University of Hong Kong in 2023. He obtained his Bachelor of Science degree in Computer Science at the Chinese University of Hong Kong in 2021. In his preultimate year, Ryan went on exchange in Nanyang Technological University in Singapore as a one-semester exchange student in Computer Science. He joined Tencent in 2021 as a Game Engineer.

His research interests include Deep Generative Models, AI + Healthcare, Protein Design

News

[12/2025] HelixFold-Design achieved picomolar-level binding affinity for minibinders at multiple targets!
[07/2025] HelixFold-S1 under review at Nature Machine Intelligence (NMI)!
[08/2024] HelixFold3 released and open source! Ryan highly engages in it!
[04/2024] Ryan joined Baidu PaddleHelix Team as a BioComputation Researcher.

Work Experience

Researcher, 04. 2024 - Present
PaddleHelix Team, Biocomputation Lab, Baidu, China
Research Assistant, 01. 2023 - 07. 2023
Project: Out-of-distribution Antibiotic Design with Pre-trained Generative Models.
Supervisor: Prof. LI Yu
Research Intern, 03. 2023 - 07. 2023
2012 Lab, Huawei Hong Kong Research Center (HKRC), Hong Kong
Game Engineer & Graphics Researcher, 08. 2021 - 07. 2022
IEG & Level Infinite Studio, Tencent, Shenzhen
Research Assistant, 05. 2020 - 05. 2021
Project: Designing Practical Schemes for Delay-Constrained Communication Tasks
Advisor: Prof. LI Cheuk Ting

Research Projects

	Biomolecular Structure Prediction with HelixFold3: Replicating the Capabilities of AlphaFold3 PaddleHelix Team [github] [paper] [online server]
	HelixFold-Design: Advanced Protein de novo Design PaddleHelix Team Yuxin Li, Yang Liu, Lihang Liu, Xianbin Ye, Xiaonan Zhang, Xiaomin Fang [paper]
	Reshaping Biomolecular Structure Prediction through Strategic Conformational Exploration with HelixFold-S1 PaddleHelix Team Lihang Liu^†, Yang Liu^†, Xianbin Ye^†, Shanzhuo Zhang, Yuxin Li, Kunrui Zhu, Yang Xue, Xiaonan Zhang, Xiaomin Fang [github] [paper] [online server]
	Antibiotic Design with Generative Models MSc Research Project Supervisor: Prof. LI Yu

Other Projects

	谈判破裂 A top-view Close Quarter Battle (CQB) 3D Shooting Game, awarded the Silver Prize of Tencent Fresh Grad Game Jam 2021.
	CUPar A partner-matching web application for CUHK Students. [GitHub]

Awards

百度 TPG NLP 部门优秀个人、AI 产品创新项目奖
Distinguished Academic Performance Scholarship 2022-23
The Silver Prize of Tencent Fresh Graduate Game Jam 2021
Yasumoto International Exchange Scholarship
Faculty of Engineering Admission Scholarship
Full Tuition Scholarship for Undergraduate Students (Mainland)